Tranexamic Acid

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seat: Beijing
Validity to: Long-term effective
Last update: 2021-07-11 19:50
Browse the number: 175
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Product details

Description


Greenway supplies tranexamic acid, which is mainly responsible for inhibiting melanin and reducing melanin, thereby preventing pigmentation and preventing dark spots from expanding. It also has the effect of inhibiting inflammation, and is effective for dullness and anti-darkness. It is a fairly multi-channel whitening ingredient. It is used as skin conditioner, moisturizer and whitening agent in cosmetics. The addition amount of this ingredient is usually between 2% and 3%. Many professional bloggers say that it also has certain benefits for rosacea. Generally speaking, it is an ingredient that is more friendly to problem skin.


Solubility


In Vitro

DMSO:≥50 mg/mL(183.65 mM)

H2O:33.33 mg/mL(122.42 mM;Need ultrasonic)

Preparing

Stock Solutions

Concentration/Solvent/Mass

1 mg

5 mg

10 mg

1 mM

6.3609ml

31.8046ml

63.6092ml

5 mM

1.2722ml

6.3069ml

12.7218ml

10 mM

0.6361ml

3.1805ml

6.3069ml

Please refer to the solubility information to select the appropriate solvent.

Tranexamic acid (Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived

plasminogen fragments with IC50 of 5 mM. Target: OthersTranexamic acid is a synthetic derivative of the amino acid lysine.

Tranexamic acid is frequently used in surgeries with high risk of blood loss such as cardiac, liver, vascular and large

orthopedic procedures. Its oral form is now being evaluated for use in outpatient conditions involving heavy

bleeding.Toxicity/Adverse event: Rare in general, including gastrointestinal effects, dizziness, fatigue, headache, and

hypersensitivity reactions. Use of tranexamic acid has a potential risk of thrombosis.

Items

Specifications

Results

Appearance

White crystalline powder

White crystalline powder

Solubility

Soluble in water and glacial acetic acid, almost not soluble in ethanol and acetone (96%)

Soluble in water and glacial acetic

acid, almost not soluble in ethanol and acetone (96%)

Identification

Infrared absorption map complies with the tranexamic acid comparison map

Infrared absorption map complies with the tranexamic acid comparison

map

PH

7.0~8.0

7.24

Loss on drying

≤0.5%

0.09%

Residue on ignition

≤0.1%

0.01%

Heavy metals

≤10ppm

<10ppm

Sulphate ash

≤0.1%

<0.03%

Chloride

≤140ppm

<140ppm

Assay

99.0%~101.0%

99.95%

A≤0.1%

A=0.043%

Related substances

B≤0.2%

C≤0.1%

B=0.0608%

C=0.009%

D≤0.1%

D=0.0051%

Total impurities(except A,B) ≤0.2%

Total impurities(except

A,B)=0.015%

Conclusion:This product conforms to requirements of BP2012 Standard.


Characteristics


1. Good stability

Compared with traditional whitening ingredients, tranexamic acid has high stability, acid and alkali resistance, and is not easily affected by temperature and environment; it does not need carrier protection, is not affected by the transmission system, and is non-irritating.

2. The skin system is easily absorbed

It is especially suitable for the effects of lightening spots, whitening and balancing the overall skin tone. In addition to lightening spots, tranexamic acid can also improve the overall skin tone transparency and the dullness of local skin patches.

3. It can dilute dark spots, yellow freckles, acne marks, etc.

Dark spots are caused by factors such as UV damage and skin aging, and the body will continue to be manufactured. Tranexamic acid reduces the production of melanin from the basal layer of the epidermis by inhibiting the activity of tyrosinase and melanocytes, and also has a redness effect on inflammation and acne marks.

4. High security

External use is non-irritating to the skin, and the highest concentration in cosmetics is 2% to 3%.


Action and effect


Tranexamic acid is often used as an important whitening ingredient in skin care quality:

Inhibit the darkening, effectively alleviate the black, red, and yellow complexion of the skin, and reduce the melanin deposition.

Effectively diminish acne marks, red blood streaks and purple spots.

Dark skin, darkening and dark circles under the eyes and yellow complexion that is unique to Asians.

Effective treatment and prevention of chloasma.

Moisturizing and hydrating, whitening skin.


http://www.greenwaybiotek.com/

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